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The 411: Growing Bones in a Lab
Found on: https://sanvada.com/2018/01/20/israeli-innovation-patient-surgery-regrow-bone/
Israeli Innovation: Patient Has Surgery to Regrow a Bone
Last month at HaEmek Hospital, located in the northern Israeli town of Afula, science fiction became science fact as groundbreaking surgery to regrow a part of a bone from a human was successfully achieved.
This feat was another demonstration of how Israeli innovation is not only changing the landscape of what technology and medicine can accomplish but how they continue to push the envelope from transforming fantasy into reality.
Danny Gets Back His Shinbone
The groundbreaking procedure was centered around a patient named Danny, who was a resident in a kibbutz that was nearby, who was in a car accident eight months ago and had a part of his shinbone taken out; the operation according to medical staff was hailed as science fiction. The surgery has been labeled as the first of its’ kind, the Yedioth Ahronoth daily reported that the doctors acquired fat cells from Danny, grew them within a lab and then injected them back into the patient’s body so that it would generate the parts that were missing of the bone. The surgery was performed at Israel’s HaEmek hospital.
Innovation from Israeli Biotechnology Company Bonus BioGroup
The innovative procedure was developed by Israeli biotechnology company Bonus BioGroup several years ago. The process involves fat cells that are divided from those cells that can generate tissue and blood vessels in which the latter are grown in a device known as a bioreactor; this device simulates the type of environment found inside a human body which provides an optimal condition for bone to regenerate. After a period of two weeks, the process produces tissue that can be transplanted in the body of the patient where it regrows the parts of the bone that is missing.
CEO of Bonus BioGroup Dr. Shai Meretzky said that we created thousands of tiny bone particles, each one of them alive, which enables us to inject them into the missing part where they join together to form a fully functional bone. The surgery was performed by the head of the orthopedic ward at HaEmek, Prof. Nimrod Rozen.
Rozen spoke with Yedioth about the surgery and commented on how important it will be regarding orthopedics. He said our patient arrived with a missing part in his shinbone that his body could not regenerate on its own. In the surgery I transplanted the cells we extracted from him two weeks ago, and within six weeks the bone will regrow itself and his shin will function normally again. This surgery is truly science fiction, it changes the entire game in orthopedics. Today I have the ability to grow any bone in a lab.
New Surgery Will Lead to Other Innovative Procedures
Rozen claims that this innovative surgery can help others, such as elderly individuals who suffer from osteoporosis and cancer patients who underwent amputations. Looking ahead to the future, he feels that the surgery could possibly be used to assist those with dwarfism become dozens of centimeters taller. According to Rozen, in every surgery I can add ten centimeters, and it can be repeated several times. This can change the self-esteem of many people.
Danny was asked how he felt after undergoing the innovative surgery and said he trusts his doctors, saying that I am sure they did a good job, and hope that in a few weeks I will be able to stand normally on my foot again. Meanwhile, a month before this surgery occurred at the same hospital, another innovative surgery took place in what was reported as part of a clinical trial. What happened was semi-liquid live bone tissue of a human that was grown within a lab from fat cells of the patient, was transplanted by an injection into the arm of the patient.
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